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| Raving is better than ranting? From MSNBC.com Night club drug could ease depression Horse tranquilizer Ketamine may be key to new treatments, study suggests updated 9:54 a.m. PT, Fri., May. 2, 2008 LONDON - Scientists have unraveled how a horse tranquilizer and hallucinogenic night club drug known as "Special K" can ease depression, researchers said on Friday. Ketamine, which can also cause feelings of detachment, could pave the way for new treatments for people suffering from depression, the researchers added. Their study, published in the Archives of General Psychiatry, found ketamine restores to normal the orbifrontal cortex, an area of the brain located above the eyes that is overactive in depressed people. The area is believed to be responsible for feelings of guilt, dread, apprehension and physical reactions such as a racing heart, said Bill Deakin, who led the study. "The study results have given us a completely novel way of treating depression and a new avenue of understanding depression," said Deakin, a neuroscientist at the University of Manchester. Depression is a leading cause of suicide and affects about 121 million people worldwide, according to the World Health Organization. In their study, Deakin and his team gave intravenous ketamine to 33 healthy male volunteers and took minute-by-minute brain scans to see what was happening as the drug took effect. Images from the scans showed that the drug — also used as a battlefield anesthetic — worked quickly, Deakin said. The results were surprising because the researchers had expected that the ketamine would instead affect the part of the brain that controls psychosis, he added. "There was some activity there but more striking was the switching off of the depression centre," Deakin said. Previous research had shown that ketamine improved symptoms in depressed people after just 24 hours — far faster than the month it can take for Prozac to kick in — but until now they did not know exactly how. The latest findings give researchers a specific target to design new drugs and offer hope for the many people who do not respond to Prozac or other standard medicines, Deakin added. Prozac was initially introduced by U.S. drugmaker Eli Lilly and Co in 1987 and belongs to a class of compounds called selective serotonin reuptake inhibitors (SSRIs). It is now off patent and widely available generically as fluoxetine. "Many people don't respond to treatment," he said in a telephone interview. "This offers a potential way of treating them." |
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| God that was so sad.
__________________ "Personally I think liberals and conservatives should move toward the middle of the road. Makes it alot easier to run'em over." (Maxine) |
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| I thought they did the same to this horse - or did they move it from the track? Poor thing - two broken ankles.....why was the jockey still makin' him run? Let's break his ankles and see how he runs!
__________________ When the goin' gets tough, the tough go shopping! |
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| From what i understand, he was trying to pull her up because she broke them after finishing. By that time, it was too late.
__________________ Tie two birds together and even though they have four wings they cannot fly. |
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| Nothing will be done ....Its a rich mans sport, and we all know that money talks etc. On the news last night they interviewed a vet and she said that running a filly with "tha boys" is totally wrong. They have to work harder and they are just as spirited, however the strength is not a match....and thats why its not a usual practice. That combined with the breeding practices, the track, the sheer don't give a crap attitude of the trainer caused that beautiful creatures death. She also explained why horses don't fair well with repair to their legs... their physical needs are such, that not being able to move naturally is a hazard to their internal organs and they usually do not survive anyway.....that is why they had to put her down so fast.. Plus the full pain had not hit her yet since she had the adrenaline going. She would have suffered greatly if they had moved her. Barbaro suffered complications from his injuries and he had to be in great pain... how the hell can they tell you...... This just sucks.
__________________ "Personally I think liberals and conservatives should move toward the middle of the road. Makes it alot easier to run'em over." (Maxine) |
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| Who's to really know who to blame? It probably wasn't all the jockey's fault - more likely the trainer, who either knew the horse's weakness or didn't know and should have. It is sure a shame.
__________________ When the goin' gets tough, the tough go shopping! |
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